Detoxication Effects of Dicarboxyl Starch on Rats Fed Strontium and Cadmium Diets

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  • FUJITA Syuzo
    Department of Food and Nutrition, Faculty of Science of Living, Osaka City University
  • TAKAYA Tomohisa
    Department of Food and Nutrition, Faculty of Science of Living, Osaka City University
  • FUWA Hidetsugu
    Department of Food and Nutrition, Faculty of Science of Living, Osaka City University

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Other Title
  • ジカルボキシルデンプンのラットに対するストロンチウムおよびカドミウムの毒性緩和効果
  • ジカルボキシル デンプン ノ ラット ニ タイスル ストロンチウム オヨビ カ

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Description

A modified starch, dicarboxyl starch (DCS), was prepared from potato starch by periodate oxida-tion following chlorite oxidation. The compound had the binding ability to metals in vitro. Under the lower nutritional level (10% casein and lower level of calcium and phosphorous), rats were fed with diets containing strontium or cadmium with or without DCS for several weeks. The growth rates of rats fed diets containing cadmium (0.005 and 0.02%) seemed to be improved by the addition of DCS. Strontium concentration in the tibia and cadmium in the liver were decreased by the addition of either 2 or 3% DCS to the diet. Strontium concentration of the tibia of rats fed the strontium diet without DCS was significantly higher than that of rats fed the strontium diet with DCS. These results indicate that DCS added to diet seemed to prevent the intestinal absorption of strontium or cadmium in rats.

Journal

  • Eiyo To Shokuryo

    Eiyo To Shokuryo 33 (2), 87-92, 1980

    JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE

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