Preparation of Liposome Using Instantaneous Vacuum-Dried Lipid Mixture

DOI Web Site Web Site 14 References

Bibliographic Information

Other Title
  • 瞬間真空乾燥脂質混合物によるリボソーム調製
  • シュンカン シンクウ カンソウ シシツ コンゴウブツ ニ ヨル リポソーム チ

Search this article

Abstract

A new method was developed for preparing liposomes using an instananeous vacuum-dried lipid mixture. White lipid powder for preparing liposomes was easily obtained by spraying an organic solution of lipids into a vacuum at a temperature exceeding the boiling point of the organic solvent. The lipid mixture thus obtained could be quite easily hydrated and converted to liposomes possessing excellent trapping efficiency and trapped volume. The liposomes thus obtained was superior to that prepared by the freeze-dry or spray-dry method. The present method showed thus be readily applicable to industrial-scale production of liposomes.

Journal

References(14)*help

See more

Details 詳細情報について

Report a problem

Back to top