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Aggressive Conservative Therapy for Refractory Ulcer with Diabetes and/or Peripheral Arterial Disease
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- Motomura Hisashi
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
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- Ohashi Natsuko
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
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- Fujikawa Heishiro
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
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- Maruyama Yoko
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
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- Suga Hisashi
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
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- Harada Teruichi
- Department of Plastic and Reconstructive Surgery, Osaka City University,Graduate School of Medicine
Bibliographic Information
- Other Title
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- 難治性足病変に対する積極的保存的療法の試み
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Description
Foot ulcer due to diabetes and/or peripheral arterial disease (PAD) frequently results in an intractable condition that is refractory to treatment. To manage such a condition, we developed a combination therapy consisting of conventional conservative therapy and surgery. This aggressive conservative treatment comprising aggressive debridement, trafermin (Fiblast Spray, Kaken, Japan) treatment and negative pressure wound therapy (NPWT) was adopted to treat 21 patients with diabetes and PAD-related refractory foot ulcer accompanied by bone exposure. Except for one patient who died during treatment, the remaining 18 patients obtained limb salvage. The mean time to cure was 5.7 months. This approach should be considered before proceeding amputation. Some patients may refuse amputation or cannot tolerate highly invasive surgical treatment including tissue transplantation. In such cases, this aggressive conservative therapy can be indicated as an excellent and repeatable technique requiring simple manipulation.
Journal
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- Japanese Journal of Surgical Wound Care
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Japanese Journal of Surgical Wound Care 2 (1), 11-19, 2011
Japan Society for Surgical Wound Care
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Details 詳細情報について
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- CRID
- 1390282680314855552
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- NII Article ID
- 130004552931
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- ISSN
- 1884880X
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed