Addressing the Unique Non-thermal Microwave Effect for Chemical Reactions in the Fields of Peptide, Oligosaccharide, Drug Library, Process and Enzymatic Syntheses

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  • マイクロ波効果を利用した全合成—ペプチド，糖鎖，創薬ライブラリ，薬剤プロセス合成，酵素合成研究を通じてマイクロ波非加熱効果に迫る—
  • マイクロ波効果を利用した全合成 : ペプチド,糖鎖,創薬ライブラリ,薬剤プロセス合成,酵素合成研究を通じてマイクロ波非加熱効果に迫る
  • マイクロハ コウカ オ リヨウ シタ ゼン ゴウセイ : ペプチド,トウ サ,ソウヤク ライブラリ,ヤクザイ プロセス ゴウセイ,コウソ ゴウセイ ケンキュウ オ ツウジテ マイクロハ ヒカネツ コウカ ニ セマル

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Abstract

The use of microwaves for the effective heating of foods is a familiar aspect of our daily lives. Beginning in 1986 and especially in the last decade, microwave irradiation has also become increasingly popular as a tool for chemical synthesis. It has mainly been used as an effective heating tool and, as a result, has allowed higher yield and/or shorter reaction times. More recently it has since suggested that microwave irradiation is not only an effective heating tool but also allows for control over other factors in chemical synthesis. Based on this premises, we have demonstrated the effective use of microwave for peptide, carbohydrate and drug library syntheses and for the development of a new process synthetic concept for Rosiglitazone preparation.

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