Synthesis of Xanthanolides Including New Acylations and Their Synthetic Applications
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- Shindo Mitsuru
- Institute for Materials Chemistry and Engineering, Kyushu University
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- Matsumoto Kenji
- Institute for Materials Chemistry and Engineering, Kyushu University
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Abstract
Xanthanolides were synthesized with intramolecular acylation of organolithium forming a seven-membered carbocycle and one-pot acylation-Wittig lactonization as key steps. The Cu(II) complex efficiently catalyzed the acylation of thioester in Wittig lactonization under neutral conditions. Using the Cu(II) catalyst, symmetric dithiomalonates were converted into dissymmetric S,O-malonates via selective monoacylation. The key step in this reaction was the thermal formation of an acylketene, the stability of which would contribute to selectivity.
Journal
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- Journal of Synthetic Organic Chemistry, Japan
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Journal of Synthetic Organic Chemistry, Japan 71 (11), 1152-1162, 2013
The Society of Synthetic Organic Chemistry, Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282680318352256
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- NII Article ID
- 130003385855
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- NII Book ID
- AN0024521X
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- COI
- 1:CAS:528:DC%2BC3sXhvVyhur%2FN
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- ISSN
- 18836526
- 00379980
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- NDL BIB ID
- 024989625
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed