Clinical experience with bicarbonate dialysis

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  • 個人用重炭酸透析液 (キンダリー液AF-DB号) の使用経験

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Dialysate containing bicarbonate, Kindaly AF-DB, was clinically used with a single patient hemodialysis system, Drake willock BD 7000, and the following results were obtained.<br>1. The pH and the composition of the supplied dialysate remained stable during a 5-6 hours dialysis session, and insoluble calcium deposition was not found.<br>2. Blood gas analysis during dialysis showed that acid-base status by bicarbonate dialysis was normalized more rapidly and physiologically than that by acetate dialysis.<br>3. Hemodynamic study suggested that bicarbonate dialysis could prevent cardiovascular instability frequently seen during acetate dialysis, and reduce that resultant symptoms during a dialysis treatment.<br>4. The extraction ratios of urea, creatinine, uric acid, as well as pre-and post-dialysis level of serum electrolytes and other blood chemistries during bicarbonate dialysis were almost same as those with acetate dialysis. The incidence of unpleasant syndrome probably related to acetate dialysis such as fatigue, nausea, hypotension was reduced significantly during bicarbonate dialysis.

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