Understanding attention-deficit/hyperactivity disorder through reward system

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  • Yahata Noriaki
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo
  • Ishii Ayaka
    Department of Pediatrics, The University of Tokyo Hospital

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  • 報酬系を通した注意欠如・多動性障害の病態理解
  • ホウシュウケイ オ トオシタ チュウイ ケツジョ ・ タドウセイ ショウガイ ノ ビョウタイ リカイ

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Attention-deficit hyperactivity disorder (ADHD) is a debilitating disorder that is characterized by developmentally subaverage levels of inattention, impulsivity and motor restlessness. Although the neurocognitive accounts for the etiology and pathophysiology of ADHD had been centered on executive dysfunctions, such as poor behavioral inhibition and cognitive interference control, recent conceptualizations of ADHD further incorporate abnormalities in the reward system, primarily in an attempt to understand the impulsive aspect of the disorder. Here we will review recent neuroimaging studies that investigated the compromised reward circuitry in patients with ADHD and how the altered functionality could be related to the symptomatology of this disorder.

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