Higher voluntary wheel running activity following endurance exercise due to oral taurine administration in mice

DOI Web Site Web Site 6 Citations 71 References Open Access

Search this article

Description

The aim of this study was to examine the effects of oral taurine (2-aminoethanesulfonic acid) administration on the amount of voluntary wheel running as an indicator of recovery from endurance exercise-induced fatigue in ICR mice. We orally administered a single dose of taurine (0.5 mg/g body weight) or physiological saline immediately after treadmill running at 25 m/min for 90 min. After administration, we placed mice in cages with a running wheel and allowed them to run freely in the wheel with free access to food. In the saline-treated group, exercise significantly decreased the amount of voluntary wheel running compared to the non-exercised mice (p < 0.01), while exercise did not decrease the amount of voluntary wheel running in the taurine-treated group. Significant effects of post-exercise taurine administration on voluntary wheel running during 6 h were found (p < 0.05). The 30-min running distance was significantly higher in the taurine-treated group than in the saline-treated group at 1-1.5 h after treadmill exercise (p < 0.05). Blood glucose and liver and skeletal muscle glycogen concentrations after treadmill exercise were similar in both groups at all times. Total food consumption during 6 h of voluntary wheel running showed no difference between the two groups. The ratio of the total running distance to total food consumption was significantly higher in the taurine-treated group than in the saline-treated group (p < 0.05). Our results show that oral taurine administration after endurance exercise increased the amount of voluntary wheel running. Taurine administration may have a positive effect on recovery from endurance exercise-induced fatigue.

Journal

Citations (6)*help

See more

References(71)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top