MIB-1 immunohistochemistry in brain tumors

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  • Nakasu Satoshi
    Department of Neurosurgery, Shiga University of Medical Science

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Other Title
  • 脳腫瘍におけるMIB-1免疫組織化学
  • ノウシュヨウ ニ オケル MIB 1 メンエキ ソシキ カガク

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Description

MIB-1 immunohistochemistry is a useful adjunct in neuropathological diagnosis. Higher MIB-1 staining indices generally correlate with increased risk of recurrence and rapid growth. However, the methodology of immunostaining and counting, and the special cut-off levels have varied considerably among studies. The author reviewed the literature to find the validity and the limitation of MIB-1 immunohistochemistry in brain tumors.

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