Long-Term Follow-Up Program and Chronic Graft-versus-Host Disease
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- Inamoto Yoshihiro
- Division of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital
Bibliographic Information
- Other Title
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- 移植後長期フォローアップと慢性GVHD
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Abstract
<p> Currently more than 5,000 hematopoietic cell transplantations are performed annually in Japan. Advances in transplantation technology have reduced early transplant-related mortality, and management of late effects after transplantation has become increasingly important for growing numbers of long-term survivors. Late effects include many complications such as chronic graft-versus-host disease (GVHD), recurrent malignancy, secondary malignancies, infection, lung diseases, endocrine diseases, cardiac diseases, chronic renal diseases, iron overload, bone diseases, and psychosocial distress. The leading causes of late mortality were recurrent malignancy, lung diseases, infection, secondary malignancies and chronic GVHD. International and domestic guidelines of preventive practices and management for long-term survivors have been published. Recent study results highlight the need for education of both patients and medical providers about late effects after transplantation, and demonstrate importance of dedicated long-term follow-up program for improving adherence to health care and long-term survival. This review focuses on evidences of long-term follow-up program, and diagnosis and treatment of chronic GVHD based on the 2014 National Institutes of Health criteria.</p>
Journal
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- Journal of Hematopoietic Cell Transplantation
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Journal of Hematopoietic Cell Transplantation 6 (2), 84-97, 2017
Japanese Society for Transplantation and Cellular Therapy
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Keywords
Details 詳細情報について
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- CRID
- 1390282680399126400
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- NII Article ID
- 130006907768
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- DOI
- 10.7889/hct.6.84
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- ISSN
- 21865612
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed