Usefulness of Coronary Flow Reserve Measurements by Echocardiography

Toyoda Tomohiko, Daimon Masao, Hasegawa Rei, Teramoto Kiyomi, Sekine Tai, Kawata Takayuki, Lee Kwangho, Maekawa Sachiko, Komuro Issei

doi:10.11262/jpnbr1987.19.1_45

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Other Title

心エコー図法による冠血流予備能測定の意義
ミニレビュー心エコー図法による冠血流予備能測定の意義
ミニレビューシンエコーズホウニヨルカンケツリュウヨビノウソクテイノイギ

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Abstract

Fundamental mechanism of myocardial ischemia is myocardial perfusion abnormality. Coronary flow reserve (CFR) has been recognized as a physiological index of the capacity to increase coronary blood flow in response to increased oxygen demand. Therefore, reduced CFR directly reflects impairment of myocardial perfusion. Clinically, positron emission tomography and Doopler guidewire by cardiac catheterization are the common methods to evaluate CFR. However, these methods are relatively expensive or invasive. Recent advance in transthoracic echocardiography has enabled us to measure CFR, especially in the left anterior descending coronary artery territory. This method has been validated by Doppler guidewire and myocardial scintigraphy, and now can be applied for the evaluation of the impairment of coronary microcirculation. CFR measurements by echocardiography is totally noninvasive, reproducible and cost effective, thus would be useful for the assessment of physiological severity of coronary artery stenosis and coronary microcirculatory disorders.

Journal

Journal of Japanese Society of Biorheology

Journal of Japanese Society of Biorheology 19 (1), 45-49, 2005

JAPANESE SOCIETY OF BIORHEOLOGY

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