A case of hemorrhagic duodenitis treated with argon plasma coagulation (APC) in hepatocellular carcinoma after proton beam radiation

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  • Takagi Kaoruko
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Hasegawa Naoyuki
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Niisato Yusuke
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Yamaura Masamichi
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Komatsu Yoshiki
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Matano Daisuke
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Iwai Kentaro
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Enami Chiaki
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Ishige Kazunori
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Fukuda Kuniaki
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Narasaka Toshiaki
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Kaneko Tsuyosi
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Abei Masato
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Hyodo Ichinosuke
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital
  • Mizokami Yuji
    Department of Gastroenterology, Tsukuba university hospital Division of Endoscopy, Tsukuba university hospital

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Other Title
  • 陽子線による放射線性十二指腸炎からの出血に対してアルゴンプラズマ凝固法が有用であった1例

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<p> Proton beam radiation is an effective treatment method for hepatocellular carcinoma. Radiation-induced duodenitis with severe hemorrhage is rare side effect by proton beam therapy. We report a case of hemorrhagic duodenitis caused by proton beam therapy for hepatocellular carcinoma, which was treated successfully with APC. A 65-year-old man, who had liver cirrhosis due to hepatitis C virus, was diagnosed hepatocellular carcinoma of right anterior segment. He received proton beam radiation. Three months later, he suffered anemia and hematochezia. Hemorrhagic duodenitis caused by proton beam radiation was found. We performed APC two times for hemorrhage from duodenitis. After the treatments, the patient had no relapse of hemorrhagic duodenitis for ten months until his death of hepatocellular carcinoma.</p>

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