A case of refractory gastrocardiac ulcer

  • Nakamura Ryuta
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Odahara Shunichi
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Uchiyama Kan
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Ishii Hironori
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Aizawa Masyu
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Sato Kenichi
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Iinuma Toshio
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Koido Shigeo
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Yamane Tateki
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Ishii Takayuki
    Department of Endoscopy, The Jikei University Kashiwa Hospital
  • Komine Kazumasa
    Department of Pathology, The Jikei University Kashiwa Hospital
  • Fujise Kiyotaka
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital
  • Tajiri Hisao
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital

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Other Title
  • PPI抵抗性胃噴門部潰瘍の1例

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Abstract

Helicobacter pylori除菌およびproton pump inhibitor (PPI)の極量連続8週投与にても治癒せず,経過中著明な周堤様隆起が発現した下掘れ型の胃噴門部潰瘍例を経験した。同潰瘍はPPIの長期投与後瘢痕化したが,減量にて再発をきたした。難治の要因として胼胝化や機械的な刺激を受けやすい部位であることなどが考えられ,経過中の隆起は肉芽組織の増生,残存による現象と推察された。

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