Temperature-dependency of electron-transport activity in mitochondria with exogenous mitochondrial DNA in Drosophila.
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- NAGATA Yuka
- Department of Biology, Ochanomizu University
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- MATSUURA Etsuko T.
- Department of Biology, Ochanomizu University
書誌事項
- 公開日
- 1991
- 資源種別
- journal article
- DOI
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- 10.1266/jjg.66.255
- 公開者
- 日本遺伝学会
この論文をさがす
説明
In mitochondrial DNA (mtDNA) heteroplasmy induced artificially in Drosophila melanogaster (Matsuura et al., 1989), foreign mtDNA derived from D. mauritiana was selectively transmitted at 25°C but was lost at 19°C (Niki et al., 1989; Matsuura et al., 1990, 1991). To investigate temperature-dependent factors in the selective transmission of mtDNA, the temperature-dependency of electron-transport activity of mitochondria from D. melanogaster in which endogenous mtDNA was completely replaced by the foreign mtDNA was compared with that of D. melanogaster and D. mauritiana. For NADH-oxidase activity, the optimum temperature of D. mauritiana mitochondria was 35°C while for two types of mitochondria from D. melanogaster each possessing either endogenous or exogenous mtDNA, maximum activity was noted at 32°C. This observation suggests that the temperature-dependency of mitochondrial electron-transport activity is mainly determined by a nuclear genome. NADH-cytochrome c reductase and cytochrome c oxidase activities were not significantly different among the three types of mitochondria. The temperature-dependency of mitochondrial function apparently is not involved in the temperature-dependent selective transmission of mtDNA in the heteroplasmic state.<br>
収録刊行物
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- 遺伝学雑誌
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遺伝学雑誌 66 (3), 255-261, 1991
日本遺伝学会
