Thermosensitive synthesis of DNA and RNA in dnaJ mutants of Escherichia coli K-12.
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- WADA Morimasa
- Department of Biology, Faculty of Science, Tokyo Metropolitan University
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- KADOKAMI Yoichi
- Institute of Life Science
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- ITIKAWA Hiraku
- Department of Biology, Faculty of Science, Tokyo Metropolitan University
Bibliographic Information
- Other Title
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- 大腸菌dnaJ(Ts)変異株のDNAおよびRNA合成の阻害について
- 大腸菌dnaJ(Ts)変異株のDNAおよびRNA合成の阻害について〔英文〕
- ダイチョウキン dnaJ Ts ヘンイシュ ノ DNA オヨビ RNA ゴウセ
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Abstract
Thermosensitive dnaJ mutants of Escherichia coli K-12 were studied with respect to their growth, nucleic acid synthesis and viability at the nonpermissive condition. Growth of the mutants was inhibited after the temperature shift, but not so severely as seen previously in the dnaK mutants. In the dnaJ mutants, both DNA and RNA syntheses were inhibited, suggesting that the conditionally defective dnaJ mutations affect both cellular DNA and RNA syntheses at the nonpermissive temperature in addition to their effects on propagation of phage lambda at the permissive temperature. DNA and RNA synthesized in the mutants at 30°C did not degrade appreciably for at least 6 hours at the nonpermissive temperature.
Journal
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- The Japanese Journal of Genetics
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The Japanese Journal of Genetics 57 (4), 407-413, 1982
The Genetics Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282680420572800
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- NII Article ID
- 130000060290
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- NII Book ID
- AA00690924
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- ISSN
- 18805787
- 0021504X
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- NDL BIB ID
- 2458719
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed