高出力半導体レーザーによる早期胃癌治療
書誌事項
- タイトル別名
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- High power diode laser treatment for early gastric cancer
- -Indocyanine green enhanced ablation method-
- -ICG を用いた生体組織吸収の修飾-
抄録
Endoscopic diode laser ablation using indocyanine green (ICG) as a photosensitizer was studied to develop the treatment for early gastric cancer. The ICG solution with Img/ml concentration was administrated to the submucosal layer. When 25W diode laser emitted with 0.2seconds repeated irradiation with 0.2seconds interval, the submucosa was not ablated because of mucosal carbonization. Histology of the specimen in this case revealed total submucosal coagulation without any proper muscle damage. When the irradiation condition was 1 seconds irradiation repeated with foot switch control with an output of 25W, the mucosa was removed and submucosa was ablated progressively. The proper muscle was intact from thermal and direct laser injury as far as the ICG containing submucosal tissue remained. We could control the ablated depth by the endoscopic observation of the ablated surface. We think our therapy might be useful for the early gastric cancer with/without the submucosal invasion, in particular inoperable case.
収録刊行物
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- 日本レーザー医学会誌
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日本レーザー医学会誌 17 (Supplement), 103-106, 1996
Japan Society for Laser Surgery and Medicine
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詳細情報 詳細情報について
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- CRID
- 1390282680431688192
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- NII論文ID
- 130004702541
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- ISSN
- 02886200
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可