Contrast-enhanced ultrasonographic features of gallbladder cancer

DOI 3 Citations 20 References
  • OSAKABE Keisuke
    Department of Medical Imaging Laboratory, Fujita Health University College
  • HORIGUCHI Yuji
    Department of Gastroenterology, Fujita Health University, School of Medicine
  • IMAI Hideo
    Department of Gastroenterology, Fujita Health University, School of Medicine
  • SAKAMOTO Hiroshi
    Department of Gastroenterology, Fujita Health University, School of Medicine
  • ICHINO Naohiro
    Department of Clinical Physiology, Fujita Health University, School of Health Sciences
  • NISHIKAWA Toru
    epartment of Clinical Laboratory, Fujita Health University Hospital

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Other Title
  • 胆嚢癌の診断における造影エコー法の有用性の検討

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Description

Contrast-enhanced ultrasonography (CEUS), using Agent Detection Imaging (ADI), is able to detect both signals from the tissue and from contrast medium. With this mode, therefore, we can evaluate vascular and perfusion patterns more precisely. In this study, diagnostic efficacies of ADI were assessed in 25 patients with gallbladder cancer, including 12 resected cases. CEUS was evaluated on tumor vascular image (TVI), tumor perfusion image (TPI), and liver parenchymal image (LPI). TVI could offer detailed structure of vessels, comparable with power Doppler image. TPI showed various patterns of perfusion: hyper-enhanced, partially-enhanced, or less-enhanced pattern. Compared with pathological findings, papillary or tubular adenocarcinoma principally showed hyper-enhancement, although squamous cell carcinoma or mucinous carcinoma showed less-enhancement. LPI, acquired 5 minutes after contrast injection, was available for evaluating direct invasion into liver parenchyma (hinf). Compared with histology of resected specimen, diagnostic accuracy of LPI was 83% in this series. In addition, CEUS was helpful for evaluating the depth of cancer invasion, because subserosal layer was demonstrable on TPI of ADI.<BR>In conclusion, CEUS was thought to be useful for localization and evaluation of extension of gallbladder cancer.

Journal

  • Tando

    Tando 19 (1), 33-41, 2005

    Japan Biliary Association

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