Retroelements: molecular features and implications for disease

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  • Jung Yi-Deun
    Department of Biological Sciences, College of Natural Sciences, Pusan National University
  • Ahn Kung
    Department of Biological Sciences, College of Natural Sciences, Pusan National University
  • Kim Yun-Ji
    Department of Biological Sciences, College of Natural Sciences, Pusan National University
  • Bae Jin-Han
    Department of Biological Sciences, College of Natural Sciences, Pusan National University
  • Lee Ja-Rang
    Department of Biological Sciences, College of Natural Sciences, Pusan National University
  • Kim Heui-Soo
    Department of Biological Sciences, College of Natural Sciences, Pusan National University

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説明

Eukaryotic genomes comprise numerous retroelements that have a major impact on the structure and regulation of gene function. Retroelements are regulated by epigenetic controls, and they generate multiple miRNAs that are involved in the induction and progression of genomic instability. Elucidation of the biological roles of retroelements deserves continuous investigation to better understand their evolutionary features and implications for disease.

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