Development of polymorphic Genetic Markers in the Quail Mhc (Coja) Region

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  • Hosomichi Kazuyoshi
    Laboratory of Animal Physiology, Faculty of Agriculture, Tokyo University of Agriculture
  • Shiina Takashi
    Department of Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine
  • Shimizu Sayako
    Department of Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine
  • Hara Hiromi
    Laboratory of Animal Physiology, Faculty of Agriculture, Tokyo University of Agriculture
  • Yoshida Yutaka
    Laboratory of Animal Physiology, Faculty of Agriculture, Tokyo University of Agriculture
  • Inoko Hidetoshi
    Department of Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine
  • Hanzawa Kei
    Laboratory of Animal Physiology, Faculty of Agriculture, Tokyo University of Agriculture

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Other Title
  • ニホンウズラMhc(Coja)領域における多型マーカーの設定

Abstract

<p>Abstract: In this research, three polymorphic repetitive sequences and three SNPs in the Coja-DMB2 and Coja-B genes were identified in the quail Mhc (Coja) region using a total of six quails derived from two lines (HTUA and LTUA lines), which were selected by plasma IgG concentration. Subsequently, polymorphism and haplotype analyses were performed on these five polymorphic markers using 39 individuals of both lines. As a result, 11 kind of Coja haplotypes were predicted. Especially, from the frequencies of Coja haplotypes the haplotype 2, 3 and 10 have difference (P=0.028) between both lines.</p>

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