CLINICAL STUDY ON CEFOTETAN IN THE FIELD OF OBSTETRICS AND GYNAECOLOGY

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  • OBATA ISAOO
    The First Department of Obstetrics and Gynaecology, Jikei University
  • IMAGAWA NOBUYUKI
    The First Department of Obstetrics and Gynaecology, Jikei University
  • OCHIAI KAZUHIKO
    The First Department of Obstetrics and Gynaecology, Jikei University
  • KOIKE KIYOHIKO
    The First Department of Obstetrics and Gynaecology, Jikei University
  • HACHIYA SHOICHI
    The First Department of Obstetrics and Gynaecology, Jikei University

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Other Title
  • 婦人科領域感染症に対するCefotetanの臨床効果
  • 産婦人科領域感染症に対するCefotetanの臨床効果
  • サンフジンカ リョウイキ カンセンショウ ニ タイスル Cefotetan ノ

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Description

A new cephamycin antibiotic, cefotetan, was administered intramuscularly to 45 patients with female genital infections including 2 cases with abscess of BARTHOLINGSL and, 14 cases with endometritis, 23 cases with adnexitis and 6 cases with pelvic peritonitis.<BR>The daily doses of the drug were 1 to 3 g, with 2 g daily being the most frequent regimen. The treatment was given twice daily in most patients.<BR>All cases responded to the drug, and marked response was seen in 22 cases and moderate response in 23.<BR>The eradication rate for causative organisms was 64.3%.<BR>In 16 cases of S. faecalis, it was rather low at 37.5%.<BR>Neither side effects nor abnormalities in clinical laboratory findings attributable to the drug were seen.

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