COMPARATIVE STUDIES ON ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CAUSATIVE ORGANISMS ISOLATED FROM PATIENTS WITH URINARY TRACT INFECTIONS (2004)
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- KUMAMOTO YOSHIAKI
- Department of Urology, Sapporo Medical University School of Medicine
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- TSUKAMOTO TAIJI
- Department of Urology, Sapporo Medical University School of Medicine
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- MATSUKAWA MASANORI
- Department of Urology, Sapporo Medical University School of Medicine
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- KUNISHIMA YASUHARU
- Department of Urology, Sapporo Medical University School of Medicine
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- HIROSE TAKAOKI
- Department of Urology, Hokkaido Social Insurance Hospital
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- SHIGETA SHIRO
- Division, Bureau of Hospital Administration, Fukushima Prefectural Goverment
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- YAMAGUCHI OSAMU
- Department of Urology, Fukushima Medical University
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- ISHIBASHI KEI
- Department of Urology, Fukushima Medical University
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- SUZUTANI TATSUO
- Department of Microbiology, Fukushima Medical University
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- YOSHIDA HIROSHI
- Department of Clinical Laboratory Medicine, Fukushima Medical University
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- IMAFUKU YUUJI
- Department of Clinical Laboratory Medicine, Fukushima Medical University
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- MURAI MASARU
- Department of Urology, Keio University School of Medicine
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- WATANABE KIYOAKI
- Central Clinical Laboratories, Keio University School of Medicine
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- KOBAYASHI YOSHIO
- Central Clinical Laboratories, Keio University School of Medicine
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- UCHIDA HIROSHI
- Central Clinical Laboratories, Keio University School of Medicine
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- MATSUDA SEIJI
- Department of Gynecology, Koto Hospital
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- SATO SHINICHI
- Department of Clinical Laboratories, Koto Hospital
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- FUJIME MAKOTO
- Department of Urology, Juntendo University School of Medicine
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- FUJITA KAZUHIKO
- Department of Urology, Juntendo University School of Medicine
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- IGARI JUN
- Urayasu Hospital, Juntendo University School of Medicine
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- OGURI TOYOKO
- Department of Clinical Laboratories, Juntendo University Hospital
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- YAMAGUCHI KEIZO
- Department of Microbiology, Toho University School of Medicine
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- FURUYA NOBUHIKO
- Department of Microbiology, Toho University School of Medicine
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- DEGUCHI TAKASHI
- Urological Devision, Disease Control Course, Gifu University Graduate School of Medicine
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- ISHIHARA SATOSHI
- Urological Devision, Disease Control Course, Gifu University Graduate School of Medicine
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- OOE HIROSHI
- Department of Urology, Kyoto Second Red Cross Hospital
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- OKA TOSHITSUGU
- Department of Urology Osaka National Hospital
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- KITAMURA MASAYA
- Department of Urology Osaka National Hospital
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- FUKUHARA YOSHIFUMI
- Department of Clinical Laboratories, Osaka National Hospital
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- KAMIDONO SADAO
- Division of Urology, Kobe University Graduate School of Medicine
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- ARAKAWA SOICHI
- Department of Surgical Operation, Kobe University Hospital
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- KUMON HIROMI
- Department of Urology, Okayama University Graduate School of Medicine and Dentistry
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- MONDEN KOICHI
- Department of Urology, Okayama University Graduate School of Medicine and Dentistry
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- MATSUMOTO TETSURO
- Department of Urology, School of Medicine, University of Occupational and Environmental Health
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- MURATANI TETSURO
- Department of Urology, School of Medicine, University of Occupational and Environmental Health
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- NAITO SEIJI
- Department of Urology, Kyushu University Graduate School of Medicine
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- EGASHIRA TOSHIHISA
- Department of Urology, Kyushu University Graduate School of Medicine
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- KONISHI TAKATOSHI
- Department of Urology, Kyushu University Graduate School of Medicine
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- KOHNO SHIGERU
- Second Department of Internal Medicine, Nagasaki University School of Medicine
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- HIRAKATA YOICHI
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- KONDO AKIRA
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- MATSUDA JUNICHI
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- NAKANO MICHIKO
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
Bibliographic Information
- Other Title
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- 尿路感染症分離菌に対する経口ならびに注射用抗菌薬の抗菌力比較 (第26報2004年)
- III. SECULAR CHANGES IN SUSCEPTIBILITY
- その3.感受性の推移
Abstract
The bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella spp.and Pseudomonas aeruginosa) isolated from patients diagnosed as urinary tract infections (UTIs) in 14 institutions in Japan were collected between August 2004 and July 2005. The susceptibilities of these bacteria to various antimicrobial agents were measured. The bacteria were divided into 2 groups consisting of uncomplicated UTIs and complicated UTIs (with and without indwelling catheter) based on their isolation origins. The results were compared with those obtained between 1995 and 2003.<BR>The drug sensitivity of S. aureus in this year was similar to those in up to the previous year and S. aureus showed the best susceptibility to vancomycin (VCM) and arbekacin (ABK). The drug sensitivity of E. faecalis in this year also was similar to those in up to the previous year. The susceptibility of E. coli to cephems in this year was generally good and was similar to those in up to the previous year. MIC90 of cefozopran (CZOP) was the most stable and 0.125μg/mL or less since 1995. The susceptibility of E. coli to cefpirome (CPR) and cefotiam (CTM) also was good but to cefaclor (CCL), cefixime (CFI), and cefpodoxime (CPDX) was largely decreased in complicated UTI groups. The sensitivity of E. coli to carbapenems also was good but to carumonam (CRMN) tended to decrease. The susceptibility of E. coli to quinolones, however, has largely changed and has decreased since 2003 in uncomplicated UTIs and 2000 in complicated UTIs. That was suggested the development of the resistance to the drug. The susceptibility of Klebsiella spp.to cefazolin (CEZ), CTM, CCL, CPDX, and cefditoren (CDTR) decreased in the previous year and recovered to the year before the previous year in this year. The susceptibility of Klebsiella spp.to other cephems was stable since 1995, especially against CZOP, the highest sensitivity (MIC90: <0.125 μg/mL) was maintained. The susceptibility of Klebsiella spp.to carbapenems and CRMN also was good. The susceptibility of Klebsiella spp.to aminoglycosides was lower than to CZOP but was stable since 1995. The susceptibility of P aeruginosa was generally low and has largely changed against the majority of the agents since 1995. The susceptibility of P. aeruginosa isolated from uncomplicated UTIs has largely changed against ceftazidime (CAZ), cefsulodin (CFS), CZOP, imipenem (IPM), meropenem (MEPM), aztreonam (AZT), CRMN, gentamicin (GM), and tobramycin (TOB). The susceptibility of P aeruginosa isolated from complicated UTIs has largely changed against CSF, CZOP, MEPM, GM, and ciprofloxacin (CPFX). The susceptibility of P aeruginosa isolated from complicated UTIs has been stable against amikacin (AMK). For annual changes in MIC50, TOB and IPM had a relatively stable and high activity (MIC50: 0.5-2 μg/mL).
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 59 (4), 217-315, 2006
Japan Antibiotics Research Association
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Details 詳細情報について
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- CRID
- 1390282680471534336
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- NII Article ID
- 130004131056
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- COI
- 1:STN:280:DC%2BD28nntlGrsg%3D%3D
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- ISSN
- 21865477
- 03682781
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed