COMPARATIVE STUDIES ON ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CAUSATIVE ORGANISMS ISOLATED FROM PATIENTS WITH URINARY TRACT INFECTIONS (2004)
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- KUMAMOTO YOSHIAKI
- Sapporo Medical University School of Medicine
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- TSUKAMOTO TAIJI
- Sapporo Medical University School of Medicine
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- MATSUKAWA MASANORI
- Sapporo Medical University School of Medicine
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- KUNISHIMA YASUHARU
- Sapporo Medical University School of Medicine
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- HIROSE TAKAOKI
- Hokkaido Social Insurance Hospital
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- SHIGETA SHIRO
- Division, Bureau of Hospital Administration, Fukushima Prefectural Goverment
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- YAMAGUTI OSAMU
- Department of Urology, Fukushima Medical University
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- ISHIBASHI KEI
- Department of Urology, Fukushima Medical University
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- SUZUTANI TATSUO
- Department of Microbiology, Fukushima Medical University
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- YOSHIDA HIROSHI
- Department of Clinical Laboratory Medicine, Fukushima Medical University
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- IMAFUKU YUUJI
- Department of Clinical Laboratory Medicine, Fukushima Medical University
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- MURAI MASARU
- Department of Urology, Keio University School of Medicine
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- WATANABE KIYOAKI
- Central Clinical Laboratories, Keio University School of Medicine
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- KOBAYASHI YOSHIO
- Central Clinical Laboratories, Keio University School of Medicine
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- UCHIDA HIROSHI
- Central Clinical Laboratories, Keio University School of Medicine
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- MATSUDA SEIJI
- Department of Gynecology, Koto Hospital
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- SATO SHINICHI
- Department of Clinical Laboratories, Koto Hospital
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- FUJIME MAKOTO
- Department of Urology, Juntendo University School of Medicine
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- FUJITA KAZUHIKO
- Department of Urology, Juntendo University School of Medicine
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- IGARI JUN
- Juntendo University School of Medicine
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- OGURI TOYOKO
- Department of Clinical Laboratories, Juntendo University Hospital
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- YAMAGUCHI KEIZO
- Department of Microbiology, Toho University School of Medicine
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- FURUYA NOBUHIKO
- Department of Microbiology, Toho University School of Medicine
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- DEGUCHI TAKASHI
- Urological Devision, Disease Control Course, Gifu University Graduate School of Medicine
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- ISHIHARA SATOSHI
- Urological Devision, Disease Control Course, Gifu University Graduate School of Medicine
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- OOE HIROSHI
- Department of Urology, Kyoto Second Red Cross Hospital
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- OKA TOSHITSUGU
- Department of Urology, Osaka National Hospital
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- KITAMURA MASAYA
- Department of Urology, Osaka National Hospital
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- FUKUHARA YOSHIFUMI
- Department of Clinical Laboratories, Osaka National Hospital
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- KAMIDONO SADAO
- Division of Urology, Kobe University Graduate School of Medicine
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- ARAKAWA SOICHI
- Department of Surgical Operation, Kobe University Hospital
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- KUMON HIROMI
- Department of Urology, Okayama University Graduate School of Medicine and Dentistry
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- MONDEN KOICHI
- Department of Urology, Okayama University Graduate School of Medicine and Dentistry
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- MATSUMOTO TETSURO
- Department of Urology, School of Medicine, University of Occupational and Environmental Health
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- MURATANI TETSURO
- Department of Urology, School of Medicine, University of Occupational and Environmental Health
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- NAITO SEIJI
- Department of Urology, Kyushu University Graduate School of Medicine
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- EGASHIRA TOSHIHISA
- Department of Urology, Kyushu University Graduate School of Medicine
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- KONISHI TAKATOSHI
- Department of Urology, Kyushu University Graduate School of Medicine
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- KOHNO SHIGERU
- Second Department of Internal Medicine, Nagasaki University School of Medicine
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- HIRAKATA YOICHI
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- KONDO AKIRA
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- MATSUDA JUNICHI
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
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- NAKANO MICHIKO
- Department of Laboratory Medicine, Nagasaki University Hospital of Medicine and Dentistry
Bibliographic Information
- Other Title
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- 尿路感染症分離菌に対する経口ならびに注射用抗菌薬の抗菌力比較 (第26報2004年)
- I. SUSCEPTIBILITY DISTRIBUTION
- その1. 感受性について
Description
The bacterial strains isolated from 490 patients diagnosed as having urinary tract infections (UTIs) in 14 institutions in Japan were collected between August 2004 and July 2005. The susceptibilities of them to many kinds of antimicrobial agents were measured. Of them, 577 strains were estimated as causative bacteria and used for the measurement. The strains consisted of 156 Gram-positive bacterial strains (27.0%) and 421 Gram-negative bacterial strains (73.0%).<BR>Against Staphylococcus aureus, arbekacin (ABK), vancomycin (VCM) showed the strongest activity and prevented the growth of all strains with 2μg/mL. Against Enterococcus faecalis, ampicillin (ABPC) and VCM showed a strong antibacterial activity. The antibacterial activity of cephems to Escherichia coli was generally good, and especially cefozopran (CZOP) and cefpirome (CPR) showed the strongest activity (MIC90: <125 μg/mL). Quinolone resistant E. coli [MIC of ciprofloxacin (CPFX): >4μg/mL] was detected at frequency of 18.8%, which was higher than that in the last year. Against Klebsiella pneumoniae, CZOP, meropenem (MEPM), and carumonam (CRMN) showed the strongest activity and prevented the growth of all strains with 0.125μg/mL or less. The antibacterial activity of the other cephems was relatively good, and decrease in their activity observed in the last year study was not recognized. Against Serratia marcescens, imipenem (IPM) and gentamicin (GM) had the strongest antibacterial activity. Against Proteus mirabilis, CRMN showed the strongest activity and prevented the growth of all strains with 0.125μg/mL or less. MEPM prevented the growth of all strains with 0.25μg/mL. Next, cefmenoxime (CMX), ceftazidime (CAZ), CZOP, cefixime (CFIX), cefpodoxime (CPDX), and cefditoren (CDTR) showed a strong activity. The antibacterial activity of the drugs to Pseudomonas aeruginosa was generally low, and MIC90 of all the drugs was ranged from 32 to >128μg/mL except IPM and MEPM having 16μg/mL. The antibacterial activities of CZOP and CAZ were considered to be relatively good on MIC50 comparison (MIC50: 2μg/mL).
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 59 (3), 177-200, 2006
Japan Antibiotics Research Association
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Details 詳細情報について
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- CRID
- 1390282680471553920
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- NII Article ID
- 130004396042
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- COI
- 1:STN:280:DC%2BD28vovFKrtQ%3D%3D
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- ISSN
- 21865477
- 03682781
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed