BACTERIA ISOLATED FROM PERFORATION PERITONITIS AND ITS ANTIMICROBIAL SUSCEPTIBILITIES

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  • 穿孔性腹膜炎からの分離菌とその薬剤感受性
  • センコウセイ フクマクエン カラ ノ ブンリキン ト ソノ ヤクザイ カンジュセイ

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Abstract

Bacteriai solatedf rom2 5 caseso f perforationp eritonitisa nd its antimicrobiaslu sceptibilitiews eres tudied. Oneh undreda nd forty-sixs trainsi ncluding3 6 strainso f aerobicb acteria, 1 07s trainso f anaerobicb acteriaa nd 3 strainso f yeastw erei solatedf romi ntra-peritoneaflu ido btaineda t operationA. monga erobicb acteria, E ntero-bacteriaceae was isolated from 13 cases (52%) out of all, and followed by those of Enterococcus spp.(24%), Pseudomonas aeruginosa (20%), in this order. Among non-spore forming anaerobic Gram-negative bacteria, the isolation rate of Bacteroides fragilis group (64%) was highest, followed by Fusobacterium spp.(40%), Prevotella spp./Porphyromonas spp.(32%) and Bilophila wadsworthia (28%), in this order. The isolation rate of non-spore forming anaerobic Gram-positive bacteria was 60%, and that of Clostridium spp. was 24%. Even by the recent advanced methods, there were 17 strains of anaerobic bacteria, which were not identified by phenotypic-identification levels. Carbapenems and β-lactams plus β-lactamase inhibitors have strong antimicrobial activities against both aerobic and anaerobic bacteria. Although metronidazole and minocycline have strong activities against anaerobic bacteria, there were many strains highly resistant to clindamycin.

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