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- YURA JIRO
- The First Department of Surgery, Nagoya City University Medical School
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- SHIMIZU YASUNOBU
- The First Department of Surgery, Nagoya City University Medical School
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- HASHIMOTO TAKASHI
- The First Department of Surgery, Nagoya City University Medical School
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- NAKAMURA TUKASA
- The First Department of Surgery, Nagoya City University Medical School
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- OTOBE YOSHIHIRO
- The First Department of Surgery, Nagoya City University Medical School
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- MINAMI MUNEHITO
- The First Department of Surgery, Nagoya City University Medical School
Bibliographic Information
- Other Title
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- 小児外科領域におけるFlomoxefの基礎的・臨床的検討
- Flomoxef周産期感染症研究会
Abstract
Basic and clinicaslt udieso f flomoxef (6315-S, FMOX) were performed in the pediatrics urgical field. The results obtained are summarized as follows:<BR>1.FMOX was administered to 7 pediatric patients with biliary atresia (FMOX 20mg/kg, i.v.d.). Peak biliaryl evels of FMOX were obtained at 1 hour after finishinag dministrationb y drip infusion, a nd were higher than those in blood 1 hours afterf inishinga dministrationb y drip infusion.<BR>2. Urinary excretion was excellent, and urinary recovery rates were 57.8-97.8%.<BR>3. FMOX was administeredt o 5 patientsi n the pediatrics urgicalf ield. One case was phlegmon, and other 4 cases were premature babiesf or postoperativper ophylactiucs e. Clinical resultwse re excellenitn 1 case, g ood in 4 cases, w ith an overalel fficacrya teo f 100%. No clinical and laboratorsy idee ffectdsu e to the administration FMOX were observed.<BR>It was concluded that FMOX was a safe and effective antibiotic in the pediatric surgical field.
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 44 (11), 1307-1312, 1991
Japan Antibiotics Research Association