COMPARATIVE STUDIES ON ACTIVITIES OF ANTIMICROBIAL AGENTS AGAINST CAUSATIVE ORGANISMS ISOLATED FROM URINARY TRACT INFECTIONS (1990)
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- KUMAMOTO YOSHIAKI
- Department of Urology, School of Medicine, Sapporo Medical College
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- HIROSE TAKAOKI
- Department of Urology, School of Medicine, Sapporo Medical College
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- TANAKA NORIAKI
- Department of Urology, School of Medicine, Sapporo Medical College
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- HIKICHI YOSHINAO
- Katta Polyclinic Hospital
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- SHIGETA SHIRO
- Department of Bacteriology, Fukushima Medical College
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- SHIRAIWA YASUO
- Department of Urology, Fukushima Medical College
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- KAMEOKA HIROSHI
- Department of Urology, Fukushima Medical College
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- YOSHIDA HIROSHI
- Department of Laboratory Medicine, Fukushima Medical College
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- OGATA MASAHIRO
- Department of Laboratory Medicine, Fukushima Medical College
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- TAZAKI HIROSHI
- Department of Urology, School of Medicine, Keio University
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- IRI HISAMI
- Central Clinical Laboratories, School of Medicine, Keio University
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- UCHIDA HIROSHI
- Central Clinical Laboratories, School of Medicine, Keio University
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- KOBAYASHI YOSHIO
- Central Clinical Laboratories, School of Medicine, Keio University
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- MATSUDA SEIJI
- Department of Gynecology, Koto Hospital
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- KITAGAWA RYUICHI
- Department of Urology, Juntendo University, School of Medicine
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- FUJIME MAKOTO
- Department of Urology, Juntendo University, School of Medicine
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- FUJITA KAZUHIKO
- Department of Urology, Juntendo University, School of Medicine
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- IGARI JUN
- Department of Clinical Pathology, Juntendo University, School of Medicine
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- OGURI TOYOKO
- Central Clinical Laboratories, Juntendo University
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- KOSAKAI NOZOMU
- Juntendo University Urayasu Hospital
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- YAMAGUCHI KEIZO
- Department of Microbiology, School of Medicine, Toho University
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- MOCHIDA CHIKAKO
- Department of Microbiology, School of Medicine, Toho University
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- FURUSAWA TARO
- Department of Urology, Kyoto Second Red Cross Hospital
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- TAKEUCHI YASUKO
- Central Clinical Laboratories, Kyoto Second Red Cross Hospital
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- MORIYAMA HIROMI
- Central Clinical Laboratories, Kyoto Second Red Cross Hospital
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- SHIBATA KIKUTARO
- Central Clinical Laboratories, Kyoto Second Red Cross Hospital
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- YONEZU SEIBUN
- The First Department of Internal Medicine, Kansai Medical University
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- TAKAHA MINATO
- Department of Urology, National Osaka Hospital
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- MATSUMIYA KIYOMI
- Department of Urology, National Osaka Hospital
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- TANAKA MICHIO
- Clinical Laboratories, National Osaka Hospital
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- KAKU MITSUO
- Department Laboratory, School of Medicine, Nagasaki University
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- SUGAWARA KAZUYUKI
- Department Laboratory, School of Medicine, Nagasaki University
Bibliographic Information
- Other Title
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- 尿路感染症分離菌に対する経口並びに注射用抗菌薬の抗菌力比較 (第12報1990年)
- I. SUSCEPTIBILITY DISTRIBUTION
- その1.感受性について
Abstract
The frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 848 bacterial strains isolated from patients with urinary tract infections in 10 hospitals during the period of June 1990 to May 1991. Of the above total bacterial isolates, Gram-positive bacteria accounted for 23.9% and a majority of them were Enterococcus faecalis. Gram-negative bacteria accounted for 76.1% and most of them were Escherichia coli.<BR>1. Enterococcus faecalis<BR>Ampicillin (ABPC), imipenem (IPM) and vancomycin (VCM) showed the highest activities against E. faecalis isolated from patients with urinary tract infections. The MIC90s of them were 2μg/ml Piperacillin (PIPC) was also active with the MIC90 of 4μg/ml. The others were not so active with the MIC90s of 32μg/ml or above.<BR>2. Staphylococcus aureus<BR>VCM and arbekacin (ABK) showed the highest activities against S. aureus isolated from patients with urinary tract infections. The MIC90s of them were 1μg/ml. The others were not so active with the MIC9s of 32μg/ml or above.<BR>3. Escherichia coli<BR>Cefozopran (CZOP), carumonam (CRMN) and ofloxacin (OFLX) showed the highest activities against E. coli isolated from patients with urinary tract infections. The MIC90s of them were of 0.125μg/ml or below. IPM, cefotiam (CTM) and cefmenoxime (CMX) were also active with the MIC90s of 0.25μg/ml. Penicillins were not so active with the MIC90s of 32μg/ml or above.<BR>4. Klebsiella pneumoniae<BR>Flomoxef (FMOX), cefixime (CFIX), CZOP and CRMN showed the highest activities against K. pneumoniae isolated from patients with urinary tract infections. The MIC90s of them were of 0.125μg/ml or below. IPM and gentamicin (GM) were also active with the MIC90s of 0.25μg/ml and 0.5μg/ml, respectively. All other cephems were also active with the MIC90s of 4μg/ml or below.<BR>5. Citrobacter freundii<BR>GM and IPM showed the highest activities against C. freundii isolated from patients with urinary tract infections. The MIC90s of them were 1μg/ml. Amikacin (AMK) was also active with the MIC90 of 4μg/ml. The others were not so active.<BR>6. Enterobacter cloacae<BR>IPM and GM showed the highest activities against E. cloacae isolated from patients with urinary tract infections. The MIC90s of them MIC90s of 0.5μg/ml. AMK and OFLX were also active with the MIC9s of 4μg/ml. Penicillins and cephems generally showed lower activities.<BR>7. Proteus mirabilis<BR>Most of the agents were active against P. mirabilis. Cephems were generally active with the MIC90s in a range of ≤0.125μg/ml-4μg/ml. CRMN, OFLX and PIPC were also active with the MIC90s in a range of ≤0.125μg/ml-0.5μg/ml. But minocycline (MINO) was not so active with the MIC90 of 64μg/ml.<BR>8. Serratia marcescens<BR>Most of the agents were not so active against S. marcescens. Comparatively, CRMN was active with the MIC90 of 16μg/ml. Penicillins and cephems were not active with the MIC90s of over than 256μg/ml.<BR>9. Pseudomonas aeruginosa<BR>Most of the agents were not so active against P. aeruginosa. IPM showed the MIC90 of 16μg/ml, CAZ, CZOP and aztreonam (AZT) showed the MIC90 of 32μg/ml.
Journal
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- The Japanese Journal of Antibiotics
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The Japanese Journal of Antibiotics 48 (10), 1295-1316, 1995
Japan Antibiotics Research Association