The effects of using a combination of Dilazep Dihydrochliride and ATP in the treatment of vertigo or dizziness

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Other Title
  • めまい症例に対する塩酸ジラゼプとATP併用効果
  • Results of blind comparative study employing an envelope method using a minor tranquilizer as the basic drug
  • マイナートランキライザーを基礎薬とした封筒法による盲検比較試験成績

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Description

The clinical efficacy of ATP and dilazep dihydrochloride was examined in patients with vertigo or dizziness of the ENT field. Fifty (50) patients with vertigo or dizziness irrespective of whether the symptoms were peripheral or central, were divided into groups of 25 patients each, including a 3-drug combination group (Group I) in which medication consisted of 300mg/day of dilazep dihydrochloride, 3g/day of ATP preparation and 15mg/day of medazepam, and a group on medazepam alone (Group II). The drugs were given for more than 4 weeks while employing the blind envelope method. In terms of subjective symptoms such as nausea and vomiting, Group I showed a significantly higher improvement rating compared to Group II (p<0.05). As for objective symptoms, a significantly higher improvement tendency in a static examination was obzerved in Group I in comparison to Group II (p<0.05). The shorter the morbid period, the higher the global improvement rating was. Based on these results, the 3-drug combination of dilazep dihydrochloride, ATP and medazepam was considered to be very useful in the treatment of vertigo or dizziness in the otolaryngological field.

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Details 詳細情報について

  • CRID
    1390282680476210176
  • NII Article ID
    130004404243
  • DOI
    10.11334/jibi1954.42.3_261
  • ISSN
    04477227
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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