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Experimental Study on the Streptomycin-Deafness
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- Makise Akihiro
- Department of Oto-rhino-laryngology, Kurume University School of Medicine
Bibliographic Information
- Other Title
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- ストレプトマイシン難聴に関する実験的研究
- The First Part: The clinical study of the preventing effect of Vitamin B<SUB>1</SUB> on the dihydrostreptomycin-deafness
- 前編 V. B<SUB>1</SUB>のDihydrostreptomycin難聴に対する予防効果に関する臨床的研究
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Description
The author has clinically observed on the various groups of DIISM-user such as the first group (37 persons without any subjective hard of hearing), the second group (11 persons who have been audiometrically examined even before application), and the third group (40 persons that DHSM and 20 mg of Vitamin B1 were simultaneously applied.)<BR>1) Six of 37 persons of the first group showed the unconscious hearing impairment at the high frequency area.<BR>2) In the observation of the change of hearing sensation before, during and after application in eleven persons of the second group, three showed the permanent loss of hearing.<BR>3) In 48 persons of the first and the second group without any subjective hearing loss, 9 (18%) showed the impairment of hearing, in which 7 revealed hearing loss by use of the total dosis below 30 g of DHSM, and in 7 cases among nine cases revealed the hearing loss at the high frequency area bilaterall and in 2 cases unilaterall.<BR>4) In the serial observation of audiometric results before, during and after the simultaneous application of DHSM and 20 mg of Vitamin B1 to 40 persons of the third group, the loss of hearing was not observed during the application, and only a case of unconscious slight hearing impairment was audiometrically seen after two months, however, in other cases any hearing complaints being not recognized.<BR>5) From the audiometrical results, it is supposed that the simultaneous use of DI-ISM and 20 mg cf Vitamin B1 can prevent the occurrence of DHSM-deafness.
Journal
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- OTOLOGIA FUKUOKA
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OTOLOGIA FUKUOKA 4 (Supplement4), 309-326, 1958
JIBI TO RINSHO KAI
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Details 詳細情報について
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- CRID
- 1390282680477058048
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- NII Article ID
- 130004404035
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- ISSN
- 04477227
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed