Effects of Chair Restraint on Plasma Enzyme Values in the Rhesus Monkey (<I>Macaca mulatta</I>)

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  • TATSUMI Tetsuo
    <I>Drug Development Laboratories, Chugai Pharmaceutical Co., Ltd.</I>
  • KOMATSU Hiromichi
    <I>Drug Development Laboratories, Chugai Pharmaceutical Co., Ltd.</I>
  • ADACHI Jiro
    <I>Drug Development Laboratories, Chugai Pharmaceutical Co., Ltd.</I>

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Other Title
  • モンキーチエア拘束がアカゲザルの血漿酵素活性値に及ぼす影響
  • モンキーチェア拘束がアカゲザルの血漿酵素活性値に及ぼす影響
  • モンキーチェア コウソク ガ アガゲザル ノ ケッショウ コウソ カッセイチ

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Description

The purpose of this paper was to examine the effect of chair restraint on plasma enzyme values in the rhesus monkey. Six monkeys were restrained to the monkey chair for eight hours. Creatine phosphokinase (CK) value increased significantly tnree hours after the onset of restraint and LDH value did eight ho, irc After the onset o restraint. The increase in CK, GOT and GPT values continued fnr 1 nr 2 days after the release from restraint. On the other hand, these plasma enzvme values in non-restraint monkeys showed almost no changes. These raesults indieate that it is necessary to establish a proper method for the adjustment to chair restraint in the rhesus monkey.

Journal

  • Experimental Animals

    Experimental Animals 39 (3), 353-359, 1990

    Japanese Association for Laboratory Animal Science

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