Tyzzer's Disease-Like Liver Lesions Observed in Young Rats

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  • TAKAGAKI Yoshio
    <I>Research Laboratories, Chugai Pharmaceutical Co. Ltd.</I>
  • TSUJI Koichiro
    <I>Research Laboratories, Chugai Pharmaceutical Co. Ltd.</I>
  • FUJIWARA Kôsaku
    <I>Department of Animal Pathology, Institute of Medical Science, University of Tokyo</I>

Bibliographic Information

Other Title
  • 幼若ラットにみられたTyzzer病様肝病変について
  • ヨウジャク ラット ニ ミラレタ Tyzzerビョウ ヨウ ギモ ビョウヘン ニ ツイテ

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Description

Multiple focal necrotic lesions were observed in the liver of 8 3-week-old rats of the same litter among 120 youngs from 15 mothers treated with a steroid hormone. The lesions resembled those observed in Tyzzer's disease of mice and many PAS-positive bacillary bodies were detected within liver cells neibouring the necrotic foci. No evident correlation was noticed between the incidence of the disease and the hormone treatment.

Journal

  • EXPERIMENTAL ANIMALS

    EXPERIMENTAL ANIMALS 17 (2), 67-69, 1968

    Japanese Association for Laboratory Animal Science

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