Use of CO<SUB>2</SUB> Euthanasia Cabinet for Experimental Animals

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Other Title
  • 実験動物安楽死用炭酸ガス箱
  • ジッケン ドウブツ アンラクシヨウ タンサン ガスバコ
  • Use of CO2 euthanasia cabinet for experimental animals

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Description

The process of CO2 euthanasia on mouse, rat, guinea pig and rabbit was observed using a CO2 euthanasia cabinet. The cabinet was filled with CO2 gas and the caged animal was placed into the cabinet. These animals quietly collapsed and their respiratory movement ceased within 25-225 seconds. A-V block was the first arrhythmia recognized on ECG in all cases. The arrhythmia recorded on ECG included complete A-V block, A-V dissociation, ventricular escape rhythm, atrial fibrillation, ventricular flutter and ventricular fibrillation. It could be concluded that euthanasia was satisfactorily performed on these species by means of the CO2 euthanasia cabinet.

Journal

  • Experimental Animals

    Experimental Animals 30 (3), 317-321, 1981

    Japanese Association for Laboratory Animal Science

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