A case report of Growing Teratoma Syndrome in a Patient with Intracranial Mixed Germ Cell Tumor

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  • Li Yi
    The department of neurosurgery kansai medical university Hirakata hospital
  • Nonaka Masahiro
    The department of neurosurgery kansai medical university Hirakata hospital
  • Noda Yukihiro
    The department of pediatrics kansai medical university Hirakata hospital
  • Kamei Takamasa
    The department of neurosurgery kansai medical university Hirakata hospital
  • Someno Yumiko
    The department of neurosurgery kansai medical university Hirakata hospital
  • Ninomiya Hideki
    The department of neurosurgery kansai medical university Hirakata hospital
  • Iwata Ryouichi
    The department of neurosurgery kansai medical university Hirakata hospital
  • Oishi Tetsuya
    The department of neurosurgery kansai medical university Hirakata hospital
  • Takeda Jyunnichi
    The department of neurosurgery kansai medical university Hirakata hospital
  • Oshige Hideyuki
    The department of neurosurgery kansai medical university Hirakata hospital
  • Yoshimura Kunikazu
    The department of neurosurgery kansai medical university Hirakata hospital
  • Asai Akio
    The department of neurosurgery kansai medical university Hirakata hospital

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Other Title
  • 放射線化学療法同期治療中にGrowing teratoma syndromeを呈した 頭蓋内混合型胚細胞腫の一例

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<p>Intracranial growing teratoma syndrome (IGTS) is a rare clinical entity, which presents with enlarging teratoma masses occurring during or after systemic chemotherapy for the treatment of nonseminomatous germ cell of the testis (NSGCT), with normalised tumor markers. We report a patient who experienced IGTS during systemic chemotherapy and radiotherapy.</p><p>The patient is a 12years old boy and the location of tumor was pineal area. Mixed Germ Cell Tumor was diagnosed by biopsy and tumor markers (AFP and HCG). Chemotherapy and radiotherapy are performed after biopsy and endoscopic third ventriculostomy(ETV). Despite the decrease in tumor marker levels to normal values, MRI examination revealed that tumor size increased. Total tumor resection are performed and histological analysis of tumor tissue only revealed a mature teratoma.</p>

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