BODY MASS INDEX AND SUBSEQUENT RISK OF HYPERTENSION, DIABETES AND HYPERCHOLESTEROLEMIA IN A POPULATION-BASED SAMPLE OF JAPANESE

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  • YAMAGISHI Kazumasa
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba
  • HOSODA Takako
    Health Science Center, Ibaraki
  • SAIRENCHI Toshimi
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba Health Service Association, Ibaraki
  • MORI Kazui
    Mito Health Center, Ibaraki
  • TOMITA Hiroshi
    Musashino-Gakuin, National Support Facility for Development of Self-sustatining Capacity
  • NISHIMURA Akio
    National Institute of Public Health
  • TANIGAWA Takeshi
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba
  • ISO Hiroyasu
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba

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Other Title
  • 地域住民における Body Mass Index と高血圧，糖尿病，高コレステロール血症発症に関する追跡研究
  • チイキ ジュウミン ニ オケル Body Mass Index ト コウケツアツ トウニョウビョウ コウコレステロール ケツショウ ハッショウ ニ カンスル ツイセキ ケンキュウ

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Objective To clarify relationships between BMI (body mass index) and the incidence of hypertension, diabetes and hypercholesterolemia among a community-based sample.<br/>Method A 4.3-year follow-up study was conducted of 1,427 men and women aged 40-69 to examine the relationships between BMI (kg/m2) and the incidence of hypertension, diabetes and hypercholesterolemia.<br/>Results During the follow-up, there were 118 cases of incident hypertension diagnosed, 56 of diabetes and 136 of hypercholesterolemia. After adjusting for sex, age, cognitive physical activity, food intake, alcohol intake, smoking, and blood pressure level, blood glucose level and serum total cholesterol level at the baseline, excess risks with the BMI category of ≥27.0 versus 21.0-22.9 were found for hypertension [relative risk (95%CI)=1.9(1.0-3.6)] and diabetes [2.9(1.2-7.4)]. However, no excess risk was evident for the 23.0-24.9 or 25.0-26.9 categories. Multivariate relative risks (95%CI) of hypercholesterolemia compared with the BMI category of 21.0-22.9 were 1.5 (0.9-2.6) for 23.0-24.9, 1.7(0.9-3.2) for 25.0-26.9 and 1.6(0.8-3.1) for ≥27.0, none of which reached statistical significance. When we combined all three diseases, the relative risks (95%CI) compared with the BMI category of 21.0-22.9 were 0.9(0.6-1.5) for 23.0-24.9, 1.2(0.7-2.1) for 25.0-26.9 and 1.8(1.0-3.3) for ≥27.0.<br/>Conclusions Increased risks of hypertension, diabetes and lifestyle-related disease were only evident with the BMI category≥27.0. Education for weight reduction should be less emphasized for persons with a BMI of 25.0-26.9 than for these with a value of ≥27.0.

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