The examination of hepatitis E after renal transplantation ―A report of four cases―

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  • NAKAGAWA Yuki
    Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital
  • SAITO Kazuhide
    Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • IKEDA Masahiro
    Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • TASAKI Masayuki
    Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • TAKAHASHI Kota
    Otukadai Clinic
  • OWADA Yohei
    Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba
  • OHSHIRO Yukio
    Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba
  • OHKOHCHI Nobuhiro
    Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba
  • OKAMOTO Hiroaki
    Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine
  • TOMITA Yoshihiko
    Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University

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Other Title
  • 腎移植後のE型肝炎の検討―4症例の経験―

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<p>Hepatitis E identified as a zoonosis with a natural reservoir in pigs.<br/> Hepatitis E virus (HEV) infection attracted close attention in Japan after the fatal case of a patient with hepatitis E was reported in 2002, and after that reports of clinical HEV infection had increased rapidly. Infection via blood transfusion leads to further increased medical concerns. Subclinical infection is the most common situation, and rare cases of HEV infection develop acute hepatitis, which results in complete recovery. There were no data on chronic hepatitis E until recently. However, in organ-transplanted patients receiving immunosuppression therapy chronicity is a possibility, and these patients need close attention.<br/> Here we report four cases that developed hepatitis E after kidney transplantation and were diagnosed in our institution. We investigated the potential route of HEV infection and present a detailed clinical course in our cases.</p>

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