Guidelines on TDM of immunosuppressive drugs in organ transplantation


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  • 免疫抑制薬TDM標準化ガイドライン2014の策定

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The Japanese Society of Therapeutic Drug Monitoring (JSTDM) and the Japanese Society of Transplantation (JST) have developed and launched the first TDM guideline to standardize the routine TDM practice for immunosuppressive drugs (ISD) used in kidney, liver and heart transplantations. This guideline describes a consensus document among transplantation experts of JST and TDM experts of the JSTDM. The Japanese version was published November 20, 2014, and its English version for publication in the TDM Journal, an official journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT), is in preparation.<br>The guideline is made up of "STATEMENTS" reporting essential information about TDM practice for immunosuppressive drugs used in Japan, which can be used in clinical settings, and of "SUMMARIES," which includes explanations and references. SUMMARIES provides reference literature as well as evidence levels and recommendation grades. Based on limitation of space, the STATEMENTS part is summarized here.


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