The utility of contrast-enhanced ultrasonography (CEUS) in pancreatic transplantation

DOI
  • Ito Taihei
    Department of Organ Transplant Surgery, Fujita Health University, School of Medicine
  • Kenmochi Takashi
    Department of Organ Transplant Surgery, Fujita Health University, School of Medicine
  • Aida Naohiro
    Department of Organ Transplant Surgery, Fujita Health University, School of Medicine
  • Ohshima Minoru
    Department of Organ Transplant Surgery, Fujita Health University, School of Medicine
  • Ono Shinichiro
    Department of Organ Transplant Surgery, Fujita Health University, School of Medicine Department of Surgery, Nagasaki University, Graduate School of Biomedical Sciences
  • Nishikawa Toru
    Division of Liver Biliary tract and Pancreas Disease, Fujita Health University, School of Medicine
  • Suzuki Atsushi
    Division of Endocrinology and Metabolism, Fujita Health University, School of Medicine
  • Hasegawa Midori
    Department of Nephrology, School of Medicine, Fujita Health University
  • Kusaka Mamoru
    Department of Urology, Fujita Health University, School of Medicine
  • Asano Takehide
    Department of Sugery, Nakano Egota Hospital
  • Hoshinaga Kiyotaka
    Department of Urology, Fujita Health University, School of Medicine
  • Matsubara Hisahiro
    Department of Frontier Surgery, Chiba University, Graduate School of Medicine

Bibliographic Information

Other Title
  • 膵臓移植における造影超音波検査（CEUS）の有用性の検討

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Description

Pancreatic graft thrombosis is the primary cause of non-immunologic graft loss, with an incidence ranging from 5% to 15%. Therefore, developing a screening test to detect graft thrombosis after pancreatic transplantation is important. We created a screening test to assess graft thrombosis after pancreatic transplantation using contrast-enhanced ultrasonography (CEUS) with Sonazoid. A total of seven patients were examined using CEUS after undergoing pancreatic transplantation. All patients were observed to have a clear blood flow in the splenic vein in the pancreatic graft, while only one of the seven patients exhibited a blood flow in the horizontal portion of the splenic vein on Doppler ultrasonography performed immediately after pancreatic transplantation. CEUS with Sonazoid demonstrated the blood flow in the splenic vein and parenchyma of the pancreatic graft in detail, in spite of the slow and lateral blood flow in the splenic vein of the pancreatic graft immediately after transplantation.<br>Evaluation of tissue blood flow in pancreatic graft using ΔTp(V-P) calculated by time intensity curve as shown by CEUS correlates with endocrine function of pancreatic graft 1 month after transplantation. These findings suggest that CEUS should become one of the novel and useful examination for pancreas transplantation.

Journal

  • Organ Biology

    Organ Biology 23 (2), 126-130, 2016

    The Japan Society for Organ Preservation and Biology

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