Principle Component Analysis of Health-Related Quality of Life Measures for Prostate Cancer

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  • KAWAHARA NORIE
    Department of Urology, Juntendo University Graduate School of Medicine Strategic Investigation on Comprehensive Cancer Network, Interfaculty Initiative in Information Studies/Graduate School of Interdisciplinary Information Studies, The University of Tokyo
  • HOTTA ZEN-U
    Strategic Investigation on Comprehensive Cancer Network, Interfaculty Initiative in Information Studies/Graduate School of Interdisciplinary Information Studies, The University of Tokyo
  • KANAYAMA MAYUKO
    Department of Urology, Juntendo University Graduate School of Medicine
  • NAGATA MASAYOSHI
    Department of Urology, Juntendo University Graduate School of Medicine
  • AKAZA HIDEYUKI
    Strategic Investigation on Comprehensive Cancer Network, Interfaculty Initiative in Information Studies/Graduate School of Interdisciplinary Information Studies, The University of Tokyo
  • HORIE SHIGEO
    Department of Urology, Juntendo University Graduate School of Medicine

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<p>Objective: The aim of this study is to elucidate underlying distinctive common features of currently used measures.</p><p>Patients: This study was conducted as a part of nationwide cross-sectional and observational study of “Prostate cancer background, quality of life (QOL), patient’s satisfaction and treatment survey by Japan Prostate Cancer Study Group (J-CaP)”. PCa survivors were invited to answer Short Form 36 (SF-36), Expanded Prostate Cancer Index Composite (EPIC), Functional Assessment of Cancer Therapy (FACT) through the web page of J-CaP. </p><p>Methods: Significant conceptual components of three health-related quality of life (HRQoL) questionnaires: EPIC, FACT, and SF-36 were identified by principle component analysis in Japanese patients. </p><p>Results: All of the questions from EPIC, FACT, and SF-36 were classified into 9 categories by principle component analysis. Our result suggests that a more feasible and integrated HRQoL measure can be created based on those components identified in our study.</p><p>Conclusion: Three HRQoL questionnaires containing 128 questions in total could be narrowed down to 9 principle components. Our future assignment is to create an integrated and more feasible version of scoring system that comprehensively covers these 9 components.</p>

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