HEMATOLOGICAL ALTERATIONS IN TUMOR-BEARING RATS, WITH REFERENCE TO PATHOGENESIS OF CHRONIC TYPE OF DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME
書誌事項
- タイトル別名
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- Hematological Alterations in Tumor bear
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Hematological studies were carried out serially in the rats transplanted subcutaneously with Yoshida ascites hepatoma AH-109A. Significant changes were observed in fibrinogen level, fibrinogen degradation products, recalcification time, platelet count, and fragmentation of red blood cells. Formation of thrombi was revealed in the vessels of tumor tissue morphologically from early stage when the tumor grew to a palpable size. Thrombi were formed also in the arterioles of the lungs in the terminal stage. Bleeding tendency was noted in some cases at death. These findings suggested the experimental induction of a type of disseminated intravascular coagulation. The systemic changes of the blood occurring in the terminal stage were preceded by localized intravascular coagulation and fibrinolysis in the tumor in early stage of tumor growth.
収録刊行物
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 68 (6), 797-804, 1977
日本癌学会
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詳細情報 詳細情報について
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- CRID
- 1390282680506043776
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- NII論文ID
- 130006409783
- 40000528951
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- NII書誌ID
- AN00045888
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- NDL書誌ID
- 1917521
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- ISSN
- 0016450X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可