EFFECT OF IODOACETAMIDE OR TWEEN 60 ON METHYLNITROSOCYANAMIDE CARCINOGENESIS IN RAT GLANDULAR AND FORESTOMACH
書誌事項
- タイトル別名
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- Effect of Iodoacetamide or Tween 60 on
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The effect of iodoacetamide or Tween 60 on carcinogenicity of methylnitrosocyanamide (MNC) in rats was examined. A significant increase in the incidence of the forestomach tumors (P<0.01) was observed in rats treated with MNC and iodoacetamide simultaneously. Moreover, there were 2 cases of glandular stomach tumors in rats treated with MNC and Tween 60 simultaneously. They were one well-differentiated adenocarcinoma and one polypoid hyperplasia. This result indicates that MNC under certain conditions is carcinogenic to the glandular stomach of rats in addition to the forestomach. Tween 60 might act by facilitating direct contact between MNC and the glandular stomach mucosa.
収録刊行物
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 68 (6), 813-818, 1977
日本癌学会
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詳細情報 詳細情報について
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- CRID
- 1390282680506048000
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- NII論文ID
- 130006409785
- 40000528967
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- NII書誌ID
- AN00045888
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- NDL書誌ID
- 1917537
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- ISSN
- 0016450X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可