Regulation of gene expression of enzymes related to glucose-metabolism by glucose in the dark in <I>Synechocystis</I> sp. PCC6803

DOI
  • Nagashima Yoshiaki
    School of Life Science, Tokyo University of Pharmacy and Life Science
  • Okada Katsuhiko
    School of Life Science, Tokyo University of Pharmacy and Life Science
  • Horii Eisuke
    School of Life Science, Tokyo University of Pharmacy and Life Science
  • Aono Fuyumi
    School of Life Science, Tokyo University of Pharmacy and Life Science
  • Tsuzuki Mikio
    School of Life Science, Tokyo University of Pharmacy and Life Science

Bibliographic Information

Other Title
  • <I>Synechocystis</I> sp. PCC6803におけるグルコース代謝関連遺伝子の発現調節 ～光要求度の低下を引き起こすヒスチジンキナーゼ様遺伝子～

Description

Effects of light on expression of one of the glycolytic enzymes, fructose-1.6-bisphosphate aldolase (fbaA) were investigated in Synechocystis sp. PCC6803. The fbaA mRNA was induced by light pulse of 5 min in the presence of glucose, while glucose addition in the dark was not effective for induction of fbaA. Therefore, both light and glucose were required for the full induction of fbaA transcription. The induction of fbaA gene expression by light pulse and glucose were inhibited by deletion of gene encoding one of the response regulators, sll1330, suggesting that sll1330 is involved in regulation of fbaA. Investigation of the effects of disruption of the genes encoding other regulatory genes indicated that there was histidine kinase whose disruption promotes fbaA expression in the absence of pulse light under glucose. These results suggest that gene expression of glycolytic enzymes are controlled through complex signal pathways interacting to each other.

Journal

Details 詳細情報について

  • CRID
    1390282680608478464
  • NII Article ID
    130006993125
  • DOI
    10.14841/jspp.2011.0.0023.0
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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