Immunotherapeutic Programs for the Treatment of Drug Abuse

DOI

Bibliographic Information

Other Title
  • 低分子化合物を標的とする抗体医薬開発の有機化学的戦略
  • Hapten Design and Synthesis
  • コカイン及びニコチン中毒に対する治療を目的として

Description

Cocaine abuse prevails as a major public health concern, causing direct adverse medical consequences and contributing to grave social problems. Nicotine is the most widely used addictive drug in the world. Despite substantial multidisplinary research, an effective treatment against these illnesses remains elusive. Immunopharmacotherapy provides a novel way for potentially treating various drug addictions. We have developed catalytic antibodies that provide a strategy for not only binding, but also degrading cocaine, which offers a broad-based therapy. We will also present the foundation for our investigations into the relationship between the conformational constraint of nicotine and its immunogenicity, and therefore the development of new nicotine vaccines.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390282680610070272
  • NII Article ID
    130006995405
  • DOI
    10.14895/hannou.29.0.124.0
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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