Contribution of Cyclopentyl Methyl Ether(CPME) to Green Chemistry and Process Innovation

DOI

Bibliographic Information

Other Title
  • 高機能エーテル系溶媒シクロペンチルメチルエーテル（CPME）によるグリーンケミストリーとプロセス革新への貢献

Description

Cyclopentyl methyl ether (CPME) is a novel high performance ether used in many manufacturing process (such as reaction, extraction and crystallization) originated from Japan and has seven unique physical properties which other ethers do not have. We will report herein some contribution of CPME to green chemistry and process innovation. Physical properties of CPME and their manufacturing process are applied under eight items of The Twelve principles of Green Chemistry and so CPME would give high contribution to that. In improved synthesis of amine by Dr. Ellman, solvent unification by CPME is useful for process innovation such as the reduction of wastes and telescoping. The toxicological assessment (PDE values provided by the GLP animal studies) and solvent selection guide in a pharmaceutical company will be also reported.

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Details 詳細情報について

  • CRID
    1390282680610346880
  • NII Article ID
    130006995745
  • DOI
    10.14895/hannou.37.0.19.0
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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