イリジウム錯体触媒を用いる水素移動型酸化反応と応用
書誌事項
- タイトル別名
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- Asymmetric Oxidative Lactonization of <i>meso</i>-Diols Catalyzed by a Chiral Ir Complex
抄録
Asymmetric oxidative lactonization of meso-diols using acetone as a cooxidant is described herein. The reaction was found to be catalyzed by 0.5 mol % of a chiral Ir complex prepared from [Cp*IrCl2]2, chiral amino alcohol and t-C4H9OK at 30 °C, giving corresponding lactones in up to 81% ee and excellent yield. A gram scale reaction was also performed without special techniques. Furthermore, an enantiomerically pure lactone was obtained by recrystallization. The reaction was successfully applied to the synthesis of various useful synthetic intermediates.
収録刊行物
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- 反応と合成の進歩シンポジウム 発表要旨概要
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反応と合成の進歩シンポジウム 発表要旨概要 30 (0), 62-63, 2004
日本薬学会化学系薬学部会
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詳細情報 詳細情報について
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- CRID
- 1390282680611754496
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- NII論文ID
- 130006997502
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可