イリジウム錯体触媒を用いる水素移動型酸化反応と応用

DOI

書誌事項

タイトル別名
  • Asymmetric Oxidative Lactonization of <i>meso</i>-Diols Catalyzed by a Chiral Ir Complex

抄録

Asymmetric oxidative lactonization of meso-diols using acetone as a cooxidant is described herein. The reaction was found to be catalyzed by 0.5 mol % of a chiral Ir complex prepared from [Cp*IrCl2]2, chiral amino alcohol and t-C4H9OK at 30 °C, giving corresponding lactones in up to 81% ee and excellent yield. A gram scale reaction was also performed without special techniques. Furthermore, an enantiomerically pure lactone was obtained by recrystallization. The reaction was successfully applied to the synthesis of various useful synthetic intermediates.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390282680611754496
  • NII論文ID
    130006997502
  • DOI
    10.14895/hannou.30.0.62.0
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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