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Effect of vitamin E intake on prostate cancer incidence : Its evaluation by meta-analysis of randomized controlled trials
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- Yabata Shogo
- Faculty of Life Sciences, Toyo University
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- Kobayashi Minako
- Graduate School of Life Sciences, Toyo University
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- Sekine Miki
- Graduate School of Life Sciences, Toyo University
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- Matsuya Kieko
- Graduate School of Life Sciences, Toyo University
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- Ota Masako
- Faculty of Life Sciences, Toyo University:Graduate School of Life Sciences, Toyo University
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- Sato Ayami
- Graduate School of Life Sciences, Toyo University
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- Yano Tomohiro
- Faculty of Life Sciences, Toyo University:Graduate School of Life Sciences, Toyo University
Bibliographic Information
- Other Title
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- 前立腺がん発症率に対するビタミンE摂取の影響 : その無作為化比較試験のメタ分析による評価
- ゼンリツセン ガン ハッショウリツ ニ タイスル ビタミン E セッシュ ノ エイキョウ ソノ ムサクイカ ヒカク シケン ノ メタ ブンセキ ニ ヨル ヒョウカ
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Description
Prostate cancer is one of the most increasing prevalence of cancers in Japan. It is well known that vitamin E acts as a useful chemo-preventive agent against several types of cancers. However there are conflicting results on a role of vitamin E in the prevention of prostate cancer. In this study, a meta-analysis of current evidence from randomized controlled trials (RCTs) was conducted to evaluate the role of vitamin E in the prevention of prostate cancer. Relevant articles in PubMed were systematically searched for RCTs of vitamin E intake and incidence of prostate cancer. From 455 potential articles, 6 eligible RCTs articles were selected. Meta-analysis of 6 RCTs identified showed no significant difference on the effect of vitamin E intake alone on the reduction in incidence of prostate cancer (Relative Risk (RR)=0.88, 95% Confidential Interval (CI): 0.71, 1.08, P=0.22; random effects). However, there was heterogeneity in this meta-analysis, so that this result suggested that vitamin E intake might have a protective effect against prostate cancer in some cases.
Journal
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- VITAMINS
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VITAMINS 87 (7), 359-363, 2013
THE VITAMIN SOCIETY OF JAPAN
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Details 詳細情報について
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- CRID
- 1390282680646175232
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- NII Article ID
- 110009624884
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- NII Book ID
- AN00207833
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- ISSN
- 2424080X
- 0006386X
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- NDL BIB ID
- 024786576
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed