STUDIES ON SUBSTANCES OF THE TOXOPYRIMIDINE GROUP : (XI) THE ACTION OF 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE

DOI
  • MORIYA Toshiro
    Department of Pediatrics, Faculty of Medicine, Osaka University

Bibliographic Information

Other Title
  • TOXOPYRIMIDINE群物質の研究 : (XI)2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINEの作用について

Abstract

The action of an agent belonging to the atoxopyrimidine group, 2-methyl-4-amino-5-amino-methylpyrimidine, on the enzyme system of the brain related to the occurrence of the running fit, (glutamic decarboxylase, γ-aminobutyric-α-ketoglutaric transaminase and pyridoxal-kinase) was studied. It was found that all of these enzymes are inhibited and the inhibition of the former two is restored by pyridoxal-phosphate. Inhibition of the former two is intensified by preincubation but in this case, recovery was observed only with γ-aminobutyric-α-ketoglutaric transaminase.

Journal

  • VITAMINS

    VITAMINS 14 (0), 90-99, 1958

    THE VITAMIN SOCIETY OF JAPAN

Details 詳細情報について

  • CRID
    1390282680710338944
  • NII Article ID
    110002860678
  • DOI
    10.20632/vso.14.0_90
  • ISSN
    2424080X
    0006386X
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top