STUDIES ON SUBSTANCES OF THE TOXOPYRIMIDINE GROUP : (XI) THE ACTION OF 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE
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- MORIYA Toshiro
- Department of Pediatrics, Faculty of Medicine, Osaka University
Bibliographic Information
- Other Title
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- TOXOPYRIMIDINE群物質の研究 : (XI)2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINEの作用について
Abstract
The action of an agent belonging to the atoxopyrimidine group, 2-methyl-4-amino-5-amino-methylpyrimidine, on the enzyme system of the brain related to the occurrence of the running fit, (glutamic decarboxylase, γ-aminobutyric-α-ketoglutaric transaminase and pyridoxal-kinase) was studied. It was found that all of these enzymes are inhibited and the inhibition of the former two is restored by pyridoxal-phosphate. Inhibition of the former two is intensified by preincubation but in this case, recovery was observed only with γ-aminobutyric-α-ketoglutaric transaminase.
Journal
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- VITAMINS
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VITAMINS 14 (0), 90-99, 1958
THE VITAMIN SOCIETY OF JAPAN
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Details 詳細情報について
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- CRID
- 1390282680710338944
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- NII Article ID
- 110002860678
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- ISSN
- 2424080X
- 0006386X
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed