The Report of Prognosis and Therapy in Sixty-one Alopecia Areata Patients

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  • Maejima Hideki
    Department of Dermatology, Kitasato University School of Medicine
  • Saito Norimitsu
    Department of Dermatology, Kitasato University School of Medicine
  • Amoh Yasuyuki
    Department of Dermatology, Kitasato University School of Medicine
  • Niiyama Shiro
    Department of Dermatology, Kitasato University School of Medicine
  • Mukuno Akira
    Department of Dermatology, Kitasato University School of Medicine
  • Katsuoka Kensei
    Department of Dermatology, Kitasato University School of Medicine

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  • 小児円形脱毛症患者61例の治療および予後に関する報告
  • ショウニ エンケイ ダツモウショウ カンジャ 61レイ ノ チリョウ オヨビ ヨゴ ニ カンスル ホウコク

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Abstract

The aim of the present study was to characterize the clinical features and prognosis of alopecia areata (AA) in pediatric patients. Subjects were 61 children with AA (30 males and 31 females) with 325 adult AA patients included as a comparison. On initial examination, 38 children had hair loss and 29 patients had atopic diathesis. The number of patients according to the pattern of hair loss was as follows: 4 mono, 11 oligo, 21 poly, 10 diffuse, 5 totalis, 7 universalis and 4 ophiasis. A total of 31 patients were treated with cryotherapy, 25 with topical SADBE, 11 with local injection with triamcinolone acetonide, and 9 with PUVA therapy. A total of 19 AA pediatric patients achieved complete hair regrowth. The convalescence rate in pediatric AA tended to be better than the convalescence rate in adult AA. Cryotherapy, topical SADBE and local injection with triamcinolone acetonide were effective in pediatric AA patients. The prevalence of atopic diathesis in children with AA may be higher than in adults with AA. We speculate that atopic diathesis may influence the prognosis of AA in children. Pediatric patients with universalis and diffuse AA did not reach convalescence; children with severe AA were more resistant to treatment than adult AA.

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