Five Cases of Symptomatic Primary HIV Infection

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  • 皮膚症状より診断に至った急性ヒト免疫不全ウイルス（HIV）感染症の5例
  • ヒフ ショウジョウ ヨリ シンダン ニ イタッタ キュウセイ ヒト メンエキ フゼン ウイルス HIV カンセンショウ ノ 5レイ

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Abstract

We report five cases of symptomatic primary HIV infection. Four of the cases were MSM (men who have sex with men). They presented with a high grade fever lasting at least 3 days, lymphadenopathy, and sore throat. Erythema without pruritus was found on their trunks and extremities. They also had whitish spots on the buccal mucosa mimicking Koplick’s buccal spot or petechia on the hard palates. Results of blood tests showed cytopenia and liver dysfunction. HIV screening tests of the fourth generation showed slightly positive reactions. Levels of HIV-1 RNA in serum were very high, indicating the presence of acute HIV infection, even though anti-HIV-1 antibodies were not detected by Western blotting assays. Although the effects of antiretroviral therapy on primary HIV infection are not established, early detection of HIV infection is important so that treatment can be started at an appropriate point. Well-timed treatment can improve quality of life by avoiding the progression into AIDS and can prevent the infection from spreading.

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