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- Hattori Tomoyasu
- Sapporo Institute for Dermatopathology Hattori Dermatology Clinic
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- Fukumoto Takaya
- Sapporo Institute for Dermatopathology
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- Anan Takashi
- Sapporo Institute for Dermatopathology
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- Kimura Tetsunori
- Sapporo Institute for Dermatopathology
Bibliographic Information
- Other Title
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- Dendritic cell neurofibroma with pseudorosettesの1例
- Dendritic cell neurofibroma with pseudorosettes ノ 1レイ
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Abstract
We report the case of a 60-year-old woman with a solitary nodule on the right cheek. Histopathologically, the lesion showed a well-circumscribed nodule in the dermis that was composed mainly of two cell types, type I and type II cells. The former were small lymphocyte-like cells with dark nuclei, and the latter were larger cells with pale vesicular nuclei and abundant eosinophilic cytoplasm. The type I cells were grouped concentrically around type II cells and formed pseudorosettes. Immunohistochemically, the type II cells and most of the type I cells were S100 protein positive, but only the type II cells were CD57 positive. Immunohistochemical studies for S100 protein and CD57 revealed that the type II cells contained copious cytoplasm endowed with a network of slender dendritic cell extensions. Based on these histopathological and immunohistochemical findings, we diagnosed our case as dendritic cell neurofibroma with pseudorosettes (DCNWPR). DCNWPR is a rare peripheral nerve sheath tumor with highly characteristic histological features; to our knowledge, this is the first case report in Japan.
Journal
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- The Japanese Journal of Dermatology
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The Japanese Journal of Dermatology 124 (2), 173-177, 2014
Japanese Dermatological Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282680714427136
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- NII Article ID
- 130003397414
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- NII Book ID
- AN00196602
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- ISSN
- 13468146
- 0021499X
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- NDL BIB ID
- 025287181
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed