A Case of <i>Mycobacterium immunogenum</i> Skin Infection Associated with Myelodysplastic Syndrome and Autoimmune Hemolytic Anemia

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  • 骨髄異形成症候群，自己免疫性溶血性貧血患者に生じた<i>Mycobacterium immunogenum</i>皮膚感染症の1例
  • 症例報告 骨髄異形成症候群,自己免疫性溶血性貧血患者に生じたMycobacterium immunogenum皮膚感染症の1例
  • ショウレイ ホウコク コツズイイケイセイ ショウコウグン,ジコ メンエキセイ ヨウケツセイ ヒンケツ カンジャ ニ ショウジタ Mycobacterium immunogenum ヒフ カンセンショウ ノ 1レイ

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Abstract

<p>An 83-year-old woman suffering from myelodysplastic syndrome and autoimmune hemolytic anemia who had been treated with oral prednisolone presented with redness, swelling, nodules, and subcutaneous indurations on the left lower leg. Mycobacteria were cultured from both a biopsy specimen and a discharge from a skin lesion and identified as Mycobacterium (M.) immunogenum by DNA sequence analysis of the 16S rRNA gene. The results of a DNA-DNA hybridization test suggested that the bacteria were M. abscessus. M. immunogenum was characterized as a new species very close to M. chelonae and M. abscessus in 2001. To our knowledge, infections due to M. immunogenum, including skin infection, have not previously been reported in Japan. However, it is possible that they have been erroneously reported as either M. chelonae or M. abscessus infections.</p>

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