Elastic-Fiber-Related Cutaneous Disorders : Their Clinical Features and Pathophysiology

  • Tajima Shingo
    Department of Dermatology, National Defense Medical College

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  • 皮膚弾力線維異常症 臨床と病態
  • 生涯教育講座 皮膚弾力線維異常症 : 臨床と病態
  • ショウガイ キョウイク コウザ ヒフ ダンリョク センイ イジョウショウ : リンショウ ト ビョウタイ

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Abstract

Elastic fibers are fibrous proteins in the dermis, then include elastin, fibrillins and microfibril-associated glycoproteins. Typical cutaneous disorders in which elastic fibers are primarily involved are pseudoxanthoma elasticum, actinic elastosis, cutis laxa, elastosis perforans serpiginosa, middermal elastolysis, and pseudoxanthoma elasticum-like papillary dermal elastolysis. Recent advances in the molecular pathology of these disorders were presented.

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