Experimental and Clinical Study of the Effects of Linear Polarized Near Infrared Light Irradiation in the Treatment of Skin Ulcers
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- Kinoshita Miyuki
- Department of Dermatology, Nihon University School of Medicine
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- Suzuki Hiroyuki
- Department of Dermatology, Nihon University School of Medicine
Bibliographic Information
- Other Title
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- 直線偏光近赤外線照射療法による皮膚潰瘍治療の実験的,臨床的検討
- チョクセン ヘンコウ キン セキガイセン ショウシャ リョウホウ ニ ヨル ヒフ カイヨウ チリョウ ノ ジッケンテキ,リンショウテキ ケントウ
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Abstract
We conducted animal and clinical studies of the usefulness of linear polarized near infrared light irradiation in the treatment of skin ulcers. The clinical investigation revealed differences in the effectiveness of this treatment method according to the etiology of skin ulcer. Healing or improvement was seen in patients with diabetic ulcers, decubitus ulcers, and burn ulcers, but no therapeutic benefits were gained for patients with stasis dermatitis or skin ulcers caused by varicose veins. This difference may be because linear polarized near infrared light irradiation is locally effective in improving blood flow in the microvasculature and promotes angiogenesis, but has minimal effects on impaired blood flow of deep veins with a caliber greater than a certain size. Animal studies showed an increase in temperature at the ulcer site within one minute after irradiation. After 5-10 days, histopathological examination disclosed angiogenesis and cell proliferation as well as a diminished ulcer area. We concluded that this therapeutic modality may be useful for treating skin ulcers and that its mechanism of action appears to involve increasing skin blood flow and promoting angiogenesis and cell proliferation.
Journal
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- The Japanese Journal of Dermatology
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The Japanese Journal of Dermatology 114 (2), 153-161, 2004
Japanese Dermatological Association
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Details 詳細情報について
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- CRID
- 1390282680716428928
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- NII Article ID
- 130004714701
- 10012952152
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- NII Book ID
- AN00196602
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- ISSN
- 13468146
- 0021499X
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- NDL BIB ID
- 025121377
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed